Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerevisiae. Although most of the SH3 domains fall into...

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Detalles Bibliográficos
Autores principales: Tonikian, Raffi, Xin, Xiaofeng, Toret, Christopher P., Gfeller, David, Landgraf, Christiane, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Currell, Bridget, Seshagiri, Somasekar, Yu, Haiyuan, Winsor, Barbara, Vidal, Marc, Gerstein, Mark B., Bader, Gary D., Volkmer, Rudolf, Cesareni, Gianni, Drubin, David G., Kim, Philip M., Sidhu, Sachdev S., Boone, Charles
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756588/
https://www.ncbi.nlm.nih.gov/pubmed/19841731
http://dx.doi.org/10.1371/journal.pbio.1000218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756588/
https://www.ncbi.nlm.nih.gov/pubmed/19841731
http://dx.doi.org/10.1371/journal.pbio.1000218

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