In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. Spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Meacham, Corbin E., Ho, Emily E., Dubrovsky, Esther, Gertler, Frank B., Hemann, Michael T.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756700/
https://www.ncbi.nlm.nih.gov/pubmed/19783987
http://dx.doi.org/10.1038/ng.451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756700/
https://www.ncbi.nlm.nih.gov/pubmed/19783987
http://dx.doi.org/10.1038/ng.451

Ejemplares similares