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cAMP Stimulates Apical Exocytosis of the Renal Na(+)-K(+)-2Cl(−) Cotransporter NKCC2 in the Thick Ascending Limb: ROLE OF PROTEIN KINASE A

The apical renal Na(+)-K(+)-2Cl(−) cotransporter NKCC2 mediates NaCl absorption by the thick ascending limb (TAL) of Henle's loop. cAMP stimulates NKCC2 by enhancing steady-state apical membrane levels of this protein; however, the trafficking and signaling mechanisms by which this occurs have...

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Detalles Bibliográficos
Autores principales: Caceres, Paulo S., Ares, Gustavo R., Ortiz, Pablo A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757200/
https://www.ncbi.nlm.nih.gov/pubmed/19592485
http://dx.doi.org/10.1074/jbc.M109.037135