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cAMP Stimulates Apical Exocytosis of the Renal Na(+)-K(+)-2Cl(−) Cotransporter NKCC2 in the Thick Ascending Limb: ROLE OF PROTEIN KINASE A
The apical renal Na(+)-K(+)-2Cl(−) cotransporter NKCC2 mediates NaCl absorption by the thick ascending limb (TAL) of Henle's loop. cAMP stimulates NKCC2 by enhancing steady-state apical membrane levels of this protein; however, the trafficking and signaling mechanisms by which this occurs have...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757200/ https://www.ncbi.nlm.nih.gov/pubmed/19592485 http://dx.doi.org/10.1074/jbc.M109.037135 |