Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity

Thyroid peroxidase (TPO) is the key enzyme in thyroid hormone production and a universal autoantigen in Graves’ and other autoimmune thyroid diseases. We wished to explore the expression of TPO and whether it was affected by thionamide antithyroid drugs. We studied recombinant TPO, stably expressed...

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Detalles Bibliográficos
Autores principales: McDonald, David O., Pearce, Simon H. S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757584/
https://www.ncbi.nlm.nih.gov/pubmed/19669106
http://dx.doi.org/10.1007/s00109-009-0511-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757584/
https://www.ncbi.nlm.nih.gov/pubmed/19669106
http://dx.doi.org/10.1007/s00109-009-0511-y

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