Towards extracellular Ca(2+) sensing by MRI: synthesis and calcium-dependent (1)H and (17)O relaxation studies of two novel bismacrocyclic Gd(3+) complexes

Two new bismacrocyclic Gd(3+) chelates containing a specific Ca(2+) binding site were synthesized as potential MRI contrast agents for the detection of Ca(2+) concentration changes at the millimolar level in the extracellular space. In the ligands, the Ca(2+)-sensitive BAPTA-bisamide central part is...

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Detalles Bibliográficos
Autores principales: Dhingra, Kirti, Fousková, Petra, Angelovski, Goran, Maier, Martin E., Logothetis, Nikos K., Tóth, Éva
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757613/
https://www.ncbi.nlm.nih.gov/pubmed/17874148
http://dx.doi.org/10.1007/s00775-007-0296-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757613/
https://www.ncbi.nlm.nih.gov/pubmed/17874148
http://dx.doi.org/10.1007/s00775-007-0296-9

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