Coxsackievirus B3 Inhibits Antigen Presentation In Vivo, Exerting a Profound and Selective Effect on the MHC Class I Pathway

Many viruses encode proteins whose major function is to evade or disable the host T cell response. Nevertheless, most viruses are readily detected by host T cells, and induce relatively strong T cell responses. Herein, we employ transgenic CD4(+) and CD8(+) T cells as sensors to evaluate in vitro an...

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Detalles Bibliográficos
Autores principales: Kemball, Christopher C., Harkins, Stephanie, Whitmire, Jason K., Flynn, Claudia T., Feuer, Ralph, Whitton, J. Lindsay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757675/
https://www.ncbi.nlm.nih.gov/pubmed/19834548
http://dx.doi.org/10.1371/journal.ppat.1000618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757675/
https://www.ncbi.nlm.nih.gov/pubmed/19834548
http://dx.doi.org/10.1371/journal.ppat.1000618

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