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Coxsackievirus B3 Inhibits Antigen Presentation In Vivo, Exerting a Profound and Selective Effect on the MHC Class I Pathway
Many viruses encode proteins whose major function is to evade or disable the host T cell response. Nevertheless, most viruses are readily detected by host T cells, and induce relatively strong T cell responses. Herein, we employ transgenic CD4(+) and CD8(+) T cells as sensors to evaluate in vitro an...
Autores principales: | Kemball, Christopher C., Harkins, Stephanie, Whitmire, Jason K., Flynn, Claudia T., Feuer, Ralph, Whitton, J. Lindsay |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757675/ https://www.ncbi.nlm.nih.gov/pubmed/19834548 http://dx.doi.org/10.1371/journal.ppat.1000618 |
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