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Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE(−/−) Mice: Effects on eNOS and Oxidative Stress
The aims of this study were to investigate the role of poly(ADP-ribose) polymerase (PARP)-1 in dyslipidemia-associated vascular dysfunction as well as autonomic nervous system dysregulation. Apolipoprotein (ApoE)(−/−) mice fed a high-fat diet were used as a model of atherosclerosis. Vascular and aut...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757717/ https://www.ncbi.nlm.nih.gov/pubmed/19823587 http://dx.doi.org/10.1371/journal.pone.0007430 |