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Induction of Membrane Ceramides: A Novel Strategy to Interfere with T Lymphocyte Cytoskeletal Reorganisation in Viral Immunosuppression

Silencing of T cell activation and function is a highly efficient strategy of immunosuppression induced by pathogens. By promoting formation of membrane microdomains essential for clustering of receptors and signalling platforms in the plasma membrane, ceramides accumulating as a result of membrane...

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Detalles Bibliográficos
Autores principales: Gassert, Evelyn, Avota, Elita, Harms, Harry, Krohne, Georg, Gulbins, Erich, Schneider-Schaulies, Sibylle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757718/
https://www.ncbi.nlm.nih.gov/pubmed/19834551
http://dx.doi.org/10.1371/journal.ppat.1000623