Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic skin inflammation in mice. Unlike similar inflammation resulting from arrest of nuclear factor κB activation in the epidermal cells, the effect induced by caspase-8 deficienc...

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Detalles Bibliográficos
Autores principales: Kovalenko, Andrew, Kim, Jin-Chul, Kang, Tae-Bong, Rajput, Akhil, Bogdanov, Konstantin, Dittrich-Breiholz, Oliver, Kracht, Michael, Brenner, Ori, Wallach, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757876/
https://www.ncbi.nlm.nih.gov/pubmed/19720838
http://dx.doi.org/10.1084/jem.20090616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757876/
https://www.ncbi.nlm.nih.gov/pubmed/19720838
http://dx.doi.org/10.1084/jem.20090616

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