TCR-dependent differentiation of thymic Foxp3(+) cells is limited to small clonal sizes

Numerous studies have highlighted the importance of high-affinity interactions between T cell receptors (TCRs) and their ligands in the selection of Foxp3(+) regulatory T cells (T reg cells). To determine the role of the TCR in directing T cells into the Foxp3(+) lineage, we generated transgenic (Tg...

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Detalles Bibliográficos
Autores principales: Leung, Monica W.L., Shen, Shiqian, Lafaille, Juan J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757883/
https://www.ncbi.nlm.nih.gov/pubmed/19737865
http://dx.doi.org/10.1084/jem.20091033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757883/
https://www.ncbi.nlm.nih.gov/pubmed/19737865
http://dx.doi.org/10.1084/jem.20091033

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