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Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology
Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are defective. Mutations in type X collagen cause metaphyseal chondrodysplasia type Schmid (MCDS), a disorder characterised by dwarfism and an expande...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757901/ https://www.ncbi.nlm.nih.gov/pubmed/19834559 http://dx.doi.org/10.1371/journal.pgen.1000691 |