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Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology

Pathologies caused by mutations in extracellular matrix proteins are generally considered to result from the synthesis of extracellular matrices that are defective. Mutations in type X collagen cause metaphyseal chondrodysplasia type Schmid (MCDS), a disorder characterised by dwarfism and an expande...

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Detalles Bibliográficos
Autores principales:	Rajpar, M. Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J., Wilson, Richard, Bateman, John F., Poulsom, Richard, Arvan, Peter, Kadler, Karl E., Briggs, Michael D., Boot-Handford, Raymond P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757901/ https://www.ncbi.nlm.nih.gov/pubmed/19834559 http://dx.doi.org/10.1371/journal.pgen.1000691

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