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Inhibition of RNA Recruitment and Replication of an RNA Virus by Acridine Derivatives with Known Anti-Prion Activities

BACKGROUND: Small molecule inhibitors of RNA virus replication are potent antiviral drugs and useful to dissect selected steps in the replication process. To identify antiviral compounds against Tomato bushy stunt virus (TBSV), a model positive stranded RNA virus, we tested acridine derivatives, suc...

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Detalles Bibliográficos
Autores principales: Sasvari, Zsuzsanna, Bach, Stéphane, Blondel, Marc, Nagy, Peter D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757906/
https://www.ncbi.nlm.nih.gov/pubmed/19823675
http://dx.doi.org/10.1371/journal.pone.0007376