Tbx22(null) mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes

Craniofacial defects involving the lip and/or palate are among the most common human birth defects. X-linked cleft palate and ankyloglossia results from loss-of-function mutations in the gene encoding the T-box transcription factor TBX22. Further studies show that TBX22 mutations are also found in a...

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Detalles Bibliográficos
Autores principales: Pauws, Erwin, Hoshino, Aya, Bentley, Lucy, Prajapati, Suresh, Keller, Charles, Hammond, Peter, Martinez-Barbera, Juan-Pedro, Moore, Gudrun E., Stanier, Philip
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758147/
https://www.ncbi.nlm.nih.gov/pubmed/19648291
http://dx.doi.org/10.1093/hmg/ddp368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758147/
https://www.ncbi.nlm.nih.gov/pubmed/19648291
http://dx.doi.org/10.1093/hmg/ddp368

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