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Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer

The monoclonal antibodies panitumumab and cetuximab that target the epidermal growth factor receptor (EGFR) have expanded the range of treatment options for metastatic colorectal cancer. Initial evaluation of these agents as monotherapy in patients with EGFR-expressing chemotherapy-refractory tumors...

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Detalles Bibliográficos
Autores principales: Siena, Salvatore, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Balfour, Julia, Bardelli, Alberto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758310/
https://www.ncbi.nlm.nih.gov/pubmed/19738166
http://dx.doi.org/10.1093/jnci/djp280