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Impairment of germline transmission after blastocyst injection with murine embryonic stem cells cultured with mouse hepatitis virus and mouse minute virus

The aim of this study was to determine the susceptibility of murine embryonic stem (mESCs) to mouse hepatitis virus (MHV-A59) and mouse minute virus (MMVp) and the effect of these viruses on germline transmission (GLT) and the serological status of recipients and pups. When recipients received 10 bl...

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Detalles Bibliográficos
Autores principales: Mahabir, E., Reindl, K., Mysliwietz, J., Needham, J., Bulian, D., Markoullis, K., Scherb, H., Schmidt, J.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758372/
https://www.ncbi.nlm.nih.gov/pubmed/18800235
http://dx.doi.org/10.1007/s11248-008-9216-1