RETRACTED ARTICLE: Age-dependent Increase in Desmosterol Restores DRM Formation and Membrane-related Functions in Cholesterol-free DHCR24(−/−) Mice

Cholesterol is a prominent modulator of the integrity and functional activity of physiological membranes and the most abundant sterol in the mammalian brain. DHCR24-knock-out mice lack cholesterol and accumulate desmosterol with age. Here we demonstrate that brain cholesterol deficiency in 3-week-ol...

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Detalles Bibliográficos
Autores principales: Kuehnle, Katrin, Ledesma, Maria D., Kalvodova, Lucie, Smith, Alicia E., Crameri, Arames, Skaanes-Brunner, Fabienne, Thelen, Karin M., Kulic, Luka, Lütjohann, Dieter, Heppner, Frank L., Nitsch, Roger M., Mohajeri, M. Hasan
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758381/
https://www.ncbi.nlm.nih.gov/pubmed/19115107
http://dx.doi.org/10.1007/s11064-008-9893-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758381/
https://www.ncbi.nlm.nih.gov/pubmed/19115107
http://dx.doi.org/10.1007/s11064-008-9893-4

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