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IL-3 and Oncogenic Abl Regulate the Myeloblast Transcriptome by Altering mRNA Stability

The growth factor interleukin-3 (IL-3) promotes the survival and growth of multipotent hematopoietic progenitors and stimulates myelopoiesis. It has also been reported to oppose terminal granulopoiesis and to support leukemic cell growth through autocrine or paracrine mechanisms. The degree to which...

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Detalles Bibliográficos
Autores principales: Ernst, Jason, Ghanem, Louis, Bar-Joseph, Ziv, McNamara, Michael, Brown, Jason, Steinman, Richard A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758590/
https://www.ncbi.nlm.nih.gov/pubmed/19829692
http://dx.doi.org/10.1371/journal.pone.0007469