High-Density SNP Screening of the Major Histocompatibility Complex in Systemic Lupus Erythematosus Demonstrates Strong Evidence for Independent Susceptibility Regions

A substantial genetic contribution to systemic lupus erythematosus (SLE) risk is conferred by major histocompatibility complex (MHC) gene(s) on chromosome 6p21. Previous studies in SLE have lacked statistical power and genetic resolution to fully define MHC influences. We characterized 1,610 Caucasi...

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Detalles Bibliográficos
Autores principales: Barcellos, Lisa F., May, Suzanne L., Ramsay, Patricia P., Quach, Hong L., Lane, Julie A., Nititham, Joanne, Noble, Janelle A., Taylor, Kimberly E., Quach, Diana L., Chung, Sharon A., Kelly, Jennifer A., Moser, Kathy L., Behrens, Timothy W., Seldin, Michael F., Thomson, Glenys, Harley, John B., Gaffney, Patrick M., Criswell, Lindsey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758598/
https://www.ncbi.nlm.nih.gov/pubmed/19851445
http://dx.doi.org/10.1371/journal.pgen.1000696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758598/
https://www.ncbi.nlm.nih.gov/pubmed/19851445
http://dx.doi.org/10.1371/journal.pgen.1000696

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