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Human Papillomavirus-16 E7 Interacts with Glutathione S-Transferase P1 and Enhances Its Role in Cell Survival

BACKGROUND: Human Papillomavirus (HPV)-16 is a paradigm for “high-risk” HPVs, the causative agents of virtually all cervical carcinomas. HPV E6 and E7 viral genes are usually expressed in these tumors, suggesting key roles for their gene products, the E6 and E7 oncoproteins, in inducing malignant tr...

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Detalles Bibliográficos
Autores principales: Mileo, Anna M., Abbruzzese, Claudia, Mattarocci, Stefano, Bellacchio, Emanuele, Pisano, Paola, Federico, Antonio, Maresca, Vittoria, Picardo, Mauro, Giorgi, Alessandra, Maras, Bruno, Schininà, M. Eugenia, Paggi, Marco G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758704/
https://www.ncbi.nlm.nih.gov/pubmed/19826491
http://dx.doi.org/10.1371/journal.pone.0007254