Cargando…

Biochemical analysis of CTLA-4 immunoreactive material from human blood

BACKGROUND: CTLA-4 was initially described as a membrane-bound molecule that inhibited lymphocyte activation by interacting with B7.1 and B7.2 molecules on antigen presenting cells. Alternative splicing of mRNA encoding the CTLA-4 receptor leads to the production of a molecule (sCTLA-4) that lacks a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tector, Matt, Khatri, Bhupendra O, Kozinski, Karen, Dennert, Kate, Oaks, Martin K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758829/
https://www.ncbi.nlm.nih.gov/pubmed/19772653
http://dx.doi.org/10.1186/1471-2172-10-51