Cargando…

Biochemical analysis of CTLA-4 immunoreactive material from human blood

BACKGROUND: CTLA-4 was initially described as a membrane-bound molecule that inhibited lymphocyte activation by interacting with B7.1 and B7.2 molecules on antigen presenting cells. Alternative splicing of mRNA encoding the CTLA-4 receptor leads to the production of a molecule (sCTLA-4) that lacks a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tector, Matt, Khatri, Bhupendra O, Kozinski, Karen, Dennert, Kate, Oaks, Martin K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758829/ https://www.ncbi.nlm.nih.gov/pubmed/19772653 http://dx.doi.org/10.1186/1471-2172-10-51

Ejemplares similares

Lack of association between sCTLA-4 levels in human plasma and common CTLA-4 polymorphisms
por: Berry, Andrew, et al.
Publicado: (2008)

Blood PD-1(+)TFh and CTLA-4(+)CD4(+) T cells predict remission after CTLA-4Ig treatment in early rheumatoid arthritis
por: Aldridge, Jonathan, et al.
Publicado: (2021)

Patients on the Transplant Waiting List Have Anti-Swine Leukocyte Antigen Class I Antibodies
por: Wang, Zheng-Yu, et al.
Publicado: (2023)

Effects of CTLA4-Ig on human monocytes
por: Tono, Toshihiro, et al.
Publicado: (2017)

Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice
por: Du, Xuexiang, et al.
Publicado: (2018)

CTLA-4: From conflict to clinic
por: Bashyam, Hema
Publicado: (2007)

The role of CTLA-4 in immune regulation
por: Verhagen, Johan, et al.
Publicado: (2008)

CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients
por: Vaddi, Prasanna Kumar, et al.
Publicado: (2023)

Identification of CTLA-4-Positive Cells in the Human Tonsil
por: Tiemann, Markus, et al.
Publicado: (2021)

Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity
por: Watanabe, Tomofumi, et al.
Publicado: (2023)

Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry
por: Rojas-Restrepo, Jessica, et al.
Publicado: (2023)

Calretinin immunoreactivity in the claustrum of the rat
por: Druga, Rastislav, et al.
Publicado: (2015)

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
por: Peggs, Karl S., et al.
Publicado: (2009)

CTLA-4 Insufficiency due to a Novel CTLA-4 Deletion, Identified through Copy Number Variation Analysis
por: Olfe, Lisa, et al.
Publicado: (2022)

Correction to: Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4‑Dependent Transendocytosis by Flow Cytometry
por: Rojas‑Restrepo, Jessica, et al.
Publicado: (2023)

Mapping of neurokinin-like immunoreactivity in the human brainstem
por: Coveñas, Rafael, et al.
Publicado: (2003)

Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract
por: Nemolato, S., et al.
Publicado: (2010)

Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain
por: O’Leary, Liam Anuj, et al.
Publicado: (2020)

CTLA4 polymorphism and primary Sjögren's syndrome
por: Lester, Susan, et al.
Publicado: (2007)

CTLA-4 based therapy (MDX-010)
por: Korman, A
Publicado: (2003)

CTLA-4 and Autoimmunity: New Twists in the Tale
por: Walker, Lucy S.K.
Publicado: (2015)

CTLA-4 in Regulatory T Cells for Cancer Immunotherapy
por: Sobhani, Navid, et al.
Publicado: (2021)

Immunoreactive cutaneous sporotrichosis()()
por: Carvalho, Gustavo de Sá Menezes, et al.
Publicado: (2020)

Ubiquitin immunoreactivity in human malignant tumours.
por: Ishibashi, Y., et al.
Publicado: (1991)

CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma
por: Hoffmann, Friederike, et al.
Publicado: (2023)

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies
por: Arce Vargas, Frederick, et al.
Publicado: (2018)

Association of CTLA4 Gene Polymorphism with Transfusion Reaction after Infusion of Leukoreduced Blood Component
por: Wen, Ying-Hao, et al.
Publicado: (2019)

(64)Cu-DOTA-Anti-CTLA-4 mAb Enabled PET Visualization of CTLA-4 on the T-Cell Infiltrating Tumor Tissues
por: Higashikawa, Kei, et al.
Publicado: (2014)

TGFβ2 Induces the Soluble Isoform of CTLA-4 – Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma
por: Khanolkar, Rahul C., et al.
Publicado: (2022)

CTLA-4 CT-60 A/G and CTLA-4 1822 C/T Gene Polymorphisms in Indonesians with Type 1 Diabetes Mellitus
por: Rochmah, Nur, et al.
Publicado: (2022)

Differences between Two Groups of Burmese Vipers (Viperidae: Azemiops) in the Proteomic Profiles, Immunoreactivity and Biochemical Functions of Their Venoms
por: Zheng, Si-Rui, et al.
Publicado: (2022)

CTLA-4 as a genetic determinant in autoimmune Addison’s disease
por: Wolff, A S B, et al.
Publicado: (2015)

Down-Regulation of CTLA-4 by HIV-1 Nef Protein
por: El-Far, Mohamed, et al.
Publicado: (2013)

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy
por: Du, Xuexiang, et al.
Publicado: (2018)

Autosomal-dominant immune dysregulation syndrome in humans with CTLA4 mutations
por: Schubert, Desirée, et al.
Publicado: (2014)

Functional Characterization of Human T Cell Hyporesponsiveness Induced by CTLA4-Ig
por: Rochman, Yrina, et al.
Publicado: (2015)

CTLA-4: a negative regulator of autoimmune disease
Publicado: (1996)

CTLA-4 blockade: therapeutic potential in cancer treatments
por: Tarhini, Ahmad A, et al.
Publicado: (2010)

Comparison of the Intracellular Trafficking Itinerary of CTLA-4 Orthologues
por: Kaur, Satdip, et al.
Publicado: (2013)

Confusing signals: Recent progress in CTLA-4 biology
por: Walker, Lucy S.K., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_d5k3uirjr20fomb2feu8istbre