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Accurate discrimination of conserved coding and non-coding regions through multiple indicators of evolutionary dynamics

BACKGROUND: The conservation of sequences between related genomes has long been recognised as an indication of functional significance and recognition of sequence homology is one of the principal approaches used in the annotation of newly sequenced genomes. In the context of recent findings that the...

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Detalles Bibliográficos
Autores principales: Rè, Matteo, Pesole, Graziano, Horner, David S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758873/
https://www.ncbi.nlm.nih.gov/pubmed/19737408
http://dx.doi.org/10.1186/1471-2105-10-282