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Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury

BACKGROUND: Contusive spinal cord injury is complicated by a delayed loss of oligodendrocytes, resulting in chronic progressive demyelination. Therefore, transplantation strategies to provide oligodendrocyte lineage cells and to enhance the extent of myelination appear to be justified for spinal cor...

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Detalles Bibliográficos
Autores principales: Hwang, Dong H, Kim, Byung G, Kim, Eun J, Lee, Seung I, Joo, In S, Suh-Kim, Haeyoung, Sohn, Seonghyang, Kim, Seung U
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758886/
https://www.ncbi.nlm.nih.gov/pubmed/19772605
http://dx.doi.org/10.1186/1471-2202-10-117