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Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalities

BACKGROUND: Koala (Koa) is a dominant mutation in mice causing bushy muzzle and pinna, and is associated with a chromosomal inversion on the distal half of chromosome 15. To identify the gene responsible for the Koa phenotypes, we investigated phenotypes of Koa homozygous mice and determined the bre...

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Detalles Bibliográficos
Autores principales: Katayama, Kentaro, Miyamoto, Sayaka, Furuno, Aki, Akiyama, Kouyou, Takahashi, Sakino, Suzuki, Hiroetsu, Tsuji, Takehito, Kunieda, Tetsuo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758895/
https://www.ncbi.nlm.nih.gov/pubmed/19772620
http://dx.doi.org/10.1186/1471-2156-10-60