Enteric Neural Crest Differentiation in Ganglioneuromas Implicates Hedgehog Signaling in Peripheral Neuroblastic Tumor Pathogenesis

Peripheral neuroblastic tumors (PNTs) share a common origin in the sympathetic nervous system, but manifest variable differentiation and growth potential. Malignant neuroblastoma (NB) and benign ganglioneuroma (GN) stand at opposite ends of the clinical spectrum. We hypothesize that a common PNT pro...

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Detalles Bibliográficos
Autores principales: Gershon, Timothy R., Shirazi, Arash, Qin, Li-Xuan, Gerald, William L., Kenney, Anna M., Cheung, Nai-Kong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759000/
https://www.ncbi.nlm.nih.gov/pubmed/19834598
http://dx.doi.org/10.1371/journal.pone.0007491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759000/
https://www.ncbi.nlm.nih.gov/pubmed/19834598
http://dx.doi.org/10.1371/journal.pone.0007491

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