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Enteric Neural Crest Differentiation in Ganglioneuromas Implicates Hedgehog Signaling in Peripheral Neuroblastic Tumor Pathogenesis
Peripheral neuroblastic tumors (PNTs) share a common origin in the sympathetic nervous system, but manifest variable differentiation and growth potential. Malignant neuroblastoma (NB) and benign ganglioneuroma (GN) stand at opposite ends of the clinical spectrum. We hypothesize that a common PNT pro...
Autores principales: | Gershon, Timothy R., Shirazi, Arash, Qin, Li-Xuan, Gerald, William L., Kenney, Anna M., Cheung, Nai-Kong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759000/ https://www.ncbi.nlm.nih.gov/pubmed/19834598 http://dx.doi.org/10.1371/journal.pone.0007491 |
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