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Direct Repeat 6 from Human Herpesvirus-6B Encodes a Nuclear Protein that Forms a Complex with the Viral DNA Processivity Factor p41

The SalI-L fragment from human herpesvirus 6A (HHV-6A) encodes a protein DR7 that has been reported to produce fibrosarcomas when injected into nude mice, to transform NIH3T3 cells, and to interact with and inhibit the function of p53. The homologous gene in HHV-6B is dr6. Since p53 is deregulated i...

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Detalles Bibliográficos
Autores principales: Schleimann, Mariane H., Møller, Janni M. L., Kofod-Olsen, Emil, Höllsberg, Per
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759074/
https://www.ncbi.nlm.nih.gov/pubmed/19829698
http://dx.doi.org/10.1371/journal.pone.0007457