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Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling

BACKGROUND: Viruses interact with and exploit the host cellular machinery for their multiplication and propagation. The MEK/ERK signaling pathway positively regulates replication of many RNA viruses. However, whether and how this signaling pathway affects hepatitis C virus (HCV) replication and prod...

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Detalles Bibliográficos
Autores principales: Ndjomou, Jean, Park, In-woo, Liu, Ying, Mayo, Lindsey D., He, Johnny J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759292/
https://www.ncbi.nlm.nih.gov/pubmed/19834602
http://dx.doi.org/10.1371/journal.pone.0007498