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Fragile X Mental Retardation Protein is Involved in Protein Synthesis-Dependent Collapse of Growth Cones Induced by Semaphorin-3A

Fragile X syndrome, the most frequent form of familial mental retardation, is caused by mutation of the Fmr1 gene. Fmr1 encodes the fragile X mental retardation protein (FMRP), an mRNA binding protein regulating local, postsynaptic mRNA translation along dendrites necessary for long-term synaptic pl...

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Detalles Bibliográficos
Autores principales: Li, Chanxia, Bassell, Gary J., Sasaki, Yukio
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759364/
https://www.ncbi.nlm.nih.gov/pubmed/19826618
http://dx.doi.org/10.3389/neuro.04.011.2009