Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression

Integrins regulate adhesion-dependent growth, survival and invasion of tumor cells. In particular, expression of integrin αvβ3 is associated with progression of a variety of human tumors. Here, we reveal a novel adhesion-independent role for integrin αvβ3 in pancreatic cancer and other carcinomas. S...

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Detalles Bibliográficos
Autores principales: Desgrosellier, Jay S, Barnes, Leo A, Shields, David J, Huang, Miller, Lau, Steven K, Prévost, Nicolas, Tarin, David, Shattil, Sanford J, Cheresh, David A
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759406/
https://www.ncbi.nlm.nih.gov/pubmed/19734908
http://dx.doi.org/10.1038/nm.2009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759406/
https://www.ncbi.nlm.nih.gov/pubmed/19734908
http://dx.doi.org/10.1038/nm.2009

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