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Identification of a PA-Binding Peptide with Inhibitory Activity against Influenza A and B Virus Replication

There is an urgent need for new drugs against influenza type A and B viruses due to incomplete protection by vaccines and the emergence of resistance to current antivirals. The influenza virus polymerase complex, consisting of the PB1, PB2 and PA subunits, represents a promising target for the devel...

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Detalles Bibliográficos
Autores principales: Wunderlich, Kerstin, Mayer, Daniel, Ranadheera, Charlene, Holler, Anne-Sophie, Mänz, Benjamin, Martin, Arnold, Chase, Geoffrey, Tegge, Werner, Frank, Ronald, Kessler, Ulrich, Schwemmle, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759517/
https://www.ncbi.nlm.nih.gov/pubmed/19841738
http://dx.doi.org/10.1371/journal.pone.0007517