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Genetic Regulation of α-Synuclein mRNA Expression in Various Human Brain Tissues

Genetic variability across the SNCA locus has been repeatedly associated with susceptibility to sporadic Parkinson's disease (PD). Accumulated evidence emphasizes the importance of SNCA dosage and expression levels in PD pathogenesis. However whether genetic variability in the SNCA gene modulat...

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Detalles Bibliográficos
Autores principales: Linnertz, Colton, Saucier, Laura, Ge, Dongliang, Cronin, Kenneth D., Burke, James R., Browndyke, Jeffrey N., Hulette, Christine M., Welsh-Bohmer, Kathleen A., Chiba-Falek, Ornit
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759540/
https://www.ncbi.nlm.nih.gov/pubmed/19834617
http://dx.doi.org/10.1371/journal.pone.0007480