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An Enhanced Single Base Extension Technique for the Analysis of Complex Viral Populations

Many techniques for the study of complex populations provide either specific information on a small number of variants or general information on the entire population. Here we describe a powerful new technique for elucidating mutation frequencies at each genomic position in a complex population. Thi...

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Detalles Bibliográficos
Autores principales: Webster, Dale R., Hekele, Armin G., Lauring, Adam S., Fischer, Kael F., Li, Hao, Andino, Raul, DeRisi, Joseph L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759544/
https://www.ncbi.nlm.nih.gov/pubmed/19834618
http://dx.doi.org/10.1371/journal.pone.0007453