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HIV-1 Infection of DC: Evidence for the Acquisition of Virus Particles from Infected T Cells by Antigen Uptake Mechanism

Dendritic cells (DC) play a pivotal role in transmission and dissemination of HIV-1. Earlier studies reported that DC present at the site of infection trap virus particles via DC-SIGN and transfer the virus to the interacting naïve T cells. This prompted us to ask the question whether DC could acqui...

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Detalles Bibliográficos
Autores principales: Venkatachari, Narasimhan J., Alber, Sean, Watkins, Simon C., Ayyavoo, Velpandi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759578/
https://www.ncbi.nlm.nih.gov/pubmed/19829715
http://dx.doi.org/10.1371/journal.pone.0007470