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Bruchpilot in Ribbon-Like Axonal Agglomerates, Behavioral Defects, and Early Death in SRPK79D Kinase Mutants of Drosophila

Defining the molecular structure and function of synapses is a central theme in brain research. In Drosophila the Bruchpilot (BRP) protein is associated with T-shaped ribbons (“T-bars”) at presynaptic active zones (AZs). BRP is required for intact AZ structure and normal evoked neurotransmitter rele...

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Detalles Bibliográficos
Autores principales: Nieratschker, Vanessa, Schubert, Alice, Jauch, Mandy, Bock, Nicole, Bucher, Daniel, Dippacher, Sonja, Krohne, Georg, Asan, Esther, Buchner, Sigrid, Buchner, Erich
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759580/
https://www.ncbi.nlm.nih.gov/pubmed/19851455
http://dx.doi.org/10.1371/journal.pgen.1000700