Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26–APC6 structure

The multi-subunit Anaphase Promoting Complex (APC) is an essential cell cycle regulator. Although CDC26 is known to play a role in APC assembly, its molecular function has remained unclear. Biophysical, structural, and genetic studies presented here reveal that CDC26 stabilizes the structure of APC6...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Dye, Billy T., Rajashankar, Kanagalaghatta R., Kurinov, Igor, Schulman, Brenda A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759704/
https://www.ncbi.nlm.nih.gov/pubmed/19668213
http://dx.doi.org/10.1038/nsmb.1645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759704/
https://www.ncbi.nlm.nih.gov/pubmed/19668213
http://dx.doi.org/10.1038/nsmb.1645

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