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Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26–APC6 structure
The multi-subunit Anaphase Promoting Complex (APC) is an essential cell cycle regulator. Although CDC26 is known to play a role in APC assembly, its molecular function has remained unclear. Biophysical, structural, and genetic studies presented here reveal that CDC26 stabilizes the structure of APC6...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759704/ https://www.ncbi.nlm.nih.gov/pubmed/19668213 http://dx.doi.org/10.1038/nsmb.1645 |