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Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like

The organizer anchors the primary embryonic axis, and balance between dorsal (organizer) and ventral domains is fundamental to body patterning. Ligand of Numb protein-X (LNX) is a RING finger and four PDZ domain containing E3 ubiquitin ligase1,2. LNX serves as a binding platform and may have a role...

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Detalles Bibliográficos
Autores principales: Ro, Hyunju, Dawid, Igor B.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759713/
https://www.ncbi.nlm.nih.gov/pubmed/19668196
http://dx.doi.org/10.1038/ncb1926