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Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers

[Image: see text] The development of a sequence-general nucleic acid copying system is an essential step in the assembly of a synthetic protocell, an autonomously replicating spatially localized chemical system capable of spontaneous Darwinian evolution. Previously described nonenzymatic template-co...

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Detalles Bibliográficos
Autores principales: Schrum, Jason P., Ricardo, Alonso, Krishnamurthy, Mathangi, Blain, J. Craig, Szostak, Jack W.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759813/
https://www.ncbi.nlm.nih.gov/pubmed/19757789
http://dx.doi.org/10.1021/ja906557v