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Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers
[Image: see text] The development of a sequence-general nucleic acid copying system is an essential step in the assembly of a synthetic protocell, an autonomously replicating spatially localized chemical system capable of spontaneous Darwinian evolution. Previously described nonenzymatic template-co...
Autores principales: | Schrum, Jason P., Ricardo, Alonso, Krishnamurthy, Mathangi, Blain, J. Craig, Szostak, Jack W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759813/ https://www.ncbi.nlm.nih.gov/pubmed/19757789 http://dx.doi.org/10.1021/ja906557v |
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