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Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer, and is the third leading cause of cancer death worldwide. Standard therapy is ineffective partly because HCC is intrinsically resistant to conventional chemotherapy. Its poor prognosis and limited treatment options make it critical...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Chua, Mei-Sze, Grepper, Susan, So, Samuel K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759906/
https://www.ncbi.nlm.nih.gov/pubmed/19778454
http://dx.doi.org/10.1186/1476-4598-8-76