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A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis
BACKGROUND: Because metabolism is fundamental in sustaining microbial life, drugs that target pathogen-specific metabolic enzymes and pathways can be very effective. In particular, the metabolic challenges faced by intracellular pathogens, such as Mycobacterium tuberculosis, residing in the infected...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759933/ https://www.ncbi.nlm.nih.gov/pubmed/19754970 http://dx.doi.org/10.1186/1752-0509-3-92 |