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A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis

BACKGROUND: Because metabolism is fundamental in sustaining microbial life, drugs that target pathogen-specific metabolic enzymes and pathways can be very effective. In particular, the metabolic challenges faced by intracellular pathogens, such as Mycobacterium tuberculosis, residing in the infected...

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Detalles Bibliográficos
Autores principales: Fang, Xin, Wallqvist, Anders, Reifman, Jaques
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759933/
https://www.ncbi.nlm.nih.gov/pubmed/19754970
http://dx.doi.org/10.1186/1752-0509-3-92