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Potential Role of Decoy B7-H4 in the Pathogenesis of Rheumatoid Arthritis: A Mouse Model Informed by Clinical Data

BACKGROUND: A pathogenic hallmark of rheumatoid arthritis (RA) is persistent inflammatory responses in target tissues and organs. Immune responses mediated by T cells and autoantibodies are known to play pivotal roles. A possible interpretation for this observation is a loss of negative regulation o...

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Detalles Bibliográficos
Autores principales: Azuma, Takeshi, Zhu, Gefeng, Xu, Haiying, Rietz, A. Cecilia, Drake, Charles G., Matteson, Eric L., Chen, Lieping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760136/
https://www.ncbi.nlm.nih.gov/pubmed/19841745
http://dx.doi.org/10.1371/journal.pmed.1000166