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Understanding the pharmacokinetics of Coartem(®)
Artemether and lumefantrine (AL), the active constituents of Coartem(® )exhibit complementary pharmacokinetic profiles. Artemether is absorbed quickly; peak concentrations of artemether and its main active metabolite, dihydroartemisinin (DHA) occur at approximately two hours post-dose, leading to a...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760239/ https://www.ncbi.nlm.nih.gov/pubmed/19818171 http://dx.doi.org/10.1186/1475-2875-8-S1-S4 |