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Converting Redox Signaling to Apoptotic Activities by Stress-Responsive Regulators HSF1 and NRF2 in Fenretinide Treated Cancer Cells

BACKGROUND: Pharmacological intervention of redox balance in cancer cells often results in oxidative stress-mediated apoptosis, attracting much attention for the development of a new generation of targeted therapy in cancer. However, little is known about mechanisms underlying the conversion from ox...

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Detalles Bibliográficos
Autores principales: Wang, Kankan, Fang, Hai, Xiao, Dakai, Zhu, Xuehua, He, Miaomiao, Pan, Xiaoling, Shi, Jiantao, Zhang, Hui, Jia, Xiaohong, Du, Yanzhi, Zhang, Ji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760443/
https://www.ncbi.nlm.nih.gov/pubmed/19844581
http://dx.doi.org/10.1371/journal.pone.0007538