Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively

BACKGROUND: The human prostacyclin receptor (hIP) undergoes agonist-induced phosphorylation, desensitisation and internalisation and may be recycled to the plasma membrane or targeted for degradation by, as yet, unknown mechanism(s). RESULTS: Herein it was sought to investigate the turnover of the h...

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Detalles Bibliográficos
Autores principales: Donnellan, Peter D, Kinsella, B Therese
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760523/
https://www.ncbi.nlm.nih.gov/pubmed/19781057
http://dx.doi.org/10.1186/1750-2187-4-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760523/
https://www.ncbi.nlm.nih.gov/pubmed/19781057
http://dx.doi.org/10.1186/1750-2187-4-7

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