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Locations and patterns of meiotic recombination in two-generation pedigrees

BACKGROUND: Meiotic crossovers are the major mechanism by which haplotypes are shuffled to generate genetic diversity. Previously available methods for the genome-wide, high-resolution identification of meiotic crossover sites are limited by the laborious nature of the assay (as in sperm typing). ME...

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Detalles Bibliográficos
Autores principales: Ting, Jason C, Roberson, Elisha DO, Currier, Duane G, Pevsner, Jonathan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760526/
https://www.ncbi.nlm.nih.gov/pubmed/19761602
http://dx.doi.org/10.1186/1471-2350-10-93