Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously

BACKGROUND: Alterations in the number of copies of genomic DNA that are common or recurrent among diseased individuals are likely to contain disease-critical genes. Unfortunately, defining common or recurrent copy number alteration (CNA) regions remains a challenge. Moreover, the heterogeneous natur...

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Detalles Bibliográficos
Autores principales: Rueda, Oscar M, Diaz-Uriarte, Ramon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760535/
https://www.ncbi.nlm.nih.gov/pubmed/19775444
http://dx.doi.org/10.1186/1471-2105-10-308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760535/
https://www.ncbi.nlm.nih.gov/pubmed/19775444
http://dx.doi.org/10.1186/1471-2105-10-308

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